Pharma companies with expertise in 5-HT3 receptors are focusing on antagonist drugs to combat nausea and vomiting in chemotherapy patients.
Many factors are at play in creating the mysterious cocktail of psychoactive chemicals found in magic mushrooms.
Magic mushrooms may be synthesizing this newly-discovered compound from baeocystin.
Binding affinity studies show psilocin and psilocybin have different preferences for serotonin receptors.
You may have heard of magic mushrooms or even consumed them. But what are they?
Data analysis and gene expression maps confirm the role of the 5-HT2A receptor in the effects of LSD.
Psilocin makes neurons grow faster and produce more connections.
A study in the mouse brain shows serotonin neurons are organized into parallel subsystems.
Seldom mentioned in scientific literature, Aeruginascin is closely structurally related to psilocybin, the most well-known psychoactive compound in "magic" mushrooms.
There are many compounds closely resembling psilocybin from a chemical structure standpoint, but pharmacological information about these psilocybin derivatives is few and far between.