Many anecdotal reports suggest that different species of magic mushrooms result in different effects for the user, but other psilocybin-like compounds present in mushrooms have been largely ignored.
"Blue bruising" is one of the most famous features of psilocybin-containing mushrooms. In this article, we explore the chemistry of blue bruising and propose a mechanism for the chemical reaction that causes this unique effect.
The metabolism of psilocybin (and psilocin) is frequently cited. But, the supporting references are seldom discussed.
Recent studies regarding the biosynthesis of psilocybin provide an answer to this age-old question.
Magic mushrooms have multiple active components including phenethylamine. These molecules are almost never acknowledged and are probably involved the pharmacology of magic mushrooms.
Psilocybin and psilocin are two different molecules found in magic mushrooms. Our current understanding is that psilocybin is inactive but rapidly converted into psilocin, which provides the observed activity.
Baeocystin is closely chemically related to psilocybin, but the scientific community has very little data on baeocystin or its human pharmacology.
On June 4, 2018, The Atlantic published Michael Pollan’s account of studying “magic” mushrooms alongside world-famous mycologist Paul Stamets. According to the story, Stamets took Pollan hunting for the Psilocybe...