Understanding the pharmacology of magic mushrooms is not just about tryptamines anymore.
Although aeruginascin is only present in psilocybin mushrooms and bufotenidine is present in toads, their structural and chemical similarities may be surprising.
Stamets says standardized formulations of multiple psilocybin analogs are the "wave of the future" because of the entourage effect.
There’s a lot more going on inside magic mushrooms than just psilocybin.
The center aims to quantify the chemicals in magic mushrooms and possibly identify new psychedelic molecules in them.
The evidence points to several possibilities. It could be psilocybin or a combination of factors.
The serotonin 5-HT2C receptor may play a key role.
There’s nausea, paralysis, and fatigue to name a few.
Aeruginascin remains an understudied compound in psychedelic research.
This study provides more evidence for the entourage effect in magic mushrooms.