Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...
The authors argue that the serotonergic mediation of estrogen has important clinical implications and warrants further investigation.
2000 Study Finds Estrogen + Progesterone Increases Cortical 5-HT2A Receptor Binding Potential in Postmenopausal Women
The hormone combination increased 5-HT2A binding potential over 20%.
The increase was seen primarily in the cerebral cortex and the nucleus accumbens.
Tetrahydrocannabiphorol could account for the pharmacological properties of some cannabis varieties which are difficult to explain by the presence of THC alone.
Eleusis’s Phase I Alzheimer’s Trial Finds Favorable Safety & Tolerability of LSD in Older Volunteers
There were no abnormalities or deviations in safety or cognitive outcome measures compared to the baseline data.
New research suggests that ketamine can aid in reorganizing alcohol-related memories.
Some changes occured to biomarkers for stress and inflammation. The subjective effects reveal more evidence of the entourage effect.