Perlolyrine is a member of the ß-carboline family of compounds.1 It is a naturally occurring metabolite found in the mycelium of fungi. It was first isolated in 1988 from Codonopsis pilosula, a perennial flowering plant in the bellflower family Campanulaceae.2  Recently, researchers isolated perlolyrine from several species of psychedelic mushrooms in the genus Psilocybe.3