August 2018
FDA Approves Psilocybin for Treatment-Resistant Depression (TRD)
The UK life science company COMPASS Pathways receives FDA approval for a clinical trial using psilocybin to treat treatment-resistant depression.
Timeline of Psychedelic Featured Events
February 1, 2012
fMRI Sees the Effects of Psilocybin on the Human Brain
Researchers find that psilocybin changes blood flow, communication pathways, and activity in the brain, enabling "a state of unconstrained cognition."
December 1, 1998
Vollenweider Finds Psychotic Effects of Psilocybin Happen via 5-HT2 Receptors
Researchers find the psychosis produced from psilocybin in humans is due to activation of serotonin 2A receptors.
1997
“TiHKAL: The Continuation” is Published
Alexander and Ann Shulgin publish "TiHKAL: The Continuation."
October 1990
“PiHKAL: A Chemical Love Story” is Published
Alexander and Ann Shulgin publish "PiHKAL: A Chemical Love Story."
October 1, 1970
CSA Places Hallucinogens on Schedule I
The Comprehensive Drug Abuse Prevention and Control Act is passed by the US Congress and psilocybin, LSD, and other hallucinogens are placed on Schedule I.
August 1960
Timothy Leary First Tries Psychedelic Mushrooms
Timothy Leary first ingests psilocybin-containing mushrooms in Cuernavaca, Mexico.
1958
Albert Hofmann Isolates Psilocybin and Psilocin
Albert Hofmann isolates psilocybin and psilocin from mushrooms.
June 1, 1957
R. Gordon Wasson Coins the Term “Magic Mushroom”
LIFE magazine publishes an article by R. Gordon Wasson called "Seeking the Magic Mushroom."
November 1, 1938
Albert Hofmann First Synthesizes LSD-25
Albert Hofmann synthesizes LSD-25 for the first time while working at Sandoz Laboratories in Switzerland.