The DEA executed search warrants and found a number of infractions in Shulgin's lab.
The Multidisciplinary Association for Psychedelic Studies is founded.
US President Richard Nixon calls drug abuse in America "public enemy number one."
Andrew Weil and Joseph Russin write a scathing critique in the Harvard Crimson about Timothy Leary and Richard Alpert's work.
Timothy Leary and Richard Alpert are fired from Harvard.
Timothy Leary first tries pure psilocybin.
Timothy Leary first ingests psilocybin-containing mushrooms in Cuernavaca, Mexico.
LIFE magazine publishes an article by R. Gordon Wasson called "Seeking the Magic Mushroom."
R. Gordon Wasson, his wife Valentina, and photographer Allan Richardson participate in a mushroom velada led by Maria Sabina.
Dr. Osmond treated over 2,000 alcoholic patients from 1954-1960 with a nearly 50% success rate.
Albert Hofmann self-tests LSD and rides his bicycle home, describing the trip as a "horror show."
Albert Hofmann synthesizes LSD-25 for the first time while working at Sandoz Laboratories in Switzerland.
American anthropologist Jean Basset Johnson and his wife Irmgard Weitlaner become the first "modern" white people to witness a mushroom velada (healing ceremony) in Huautla, Mexico.
Science magazine publishes a first-hand psilocybin experience written by a botanist calling himself "Mr. W."
Europeans discover the Xochipilli Prince of Flowers statue which has carvings of Psilocybe.
Dr. Everard Brande of London, England is the first to document the effects of psychedelic mushrooms on humans in a medical journal.
Dr. William Heberden writes in the Gentleman's Magazine about the behavior of a family after eating mushrooms.
Florentine Codex is Published and Contains Description of Aztecs Using Peyote and Hallucinogenic Mushrooms
Spanish priest Bernardino de Sahagùn writes in the Florentine Codex about the Aztecs using peyote and hallucinogenic mushrooms.
Catholic priests punish native Mexicans for using entheogens.
Physician Pieter van Foreest describes the behavior of a woman after eating mushrooms.
The Codex Magliabecchiano is written and contains at least one illustration showing teonanacátl mushrooms.
The Mixtec Mesoamerican Codex shows the ritual use of mushrooms by Mixtec gods.
Chang Hua's "Record of Investigation of Things" (Po Wu Chih) describes what could be the use of hallucinogenic mushrooms during the Chin (Jin)Dynasty.
A mural in the Selva Pascuala cave near Villar del Humo, Spain depicts what researchers believe are Psilocybe hispanica mushrooms.
Cave art in Tassili n'Ajjer SE Algeria shows the oldest known petroglyphs of psychoactive mushrooms, specifically Psilocybe.