The Structure and Function of the Serotonin 5-HT1A Receptor
Activation of neuronal 5-HT1A receptors causes hyperpolarization and inhibition of cellular signaling.
Articles
Washington, DC Moves to Decriminalize Naturally Occurring Psychedelics
Decriminalize Nature DC is driving the effort to get the initiative on the November ballot.
The Structure-Activity Relationship of Two Kratom Compounds
Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
UK Assessment Agency Rejects Spravato Ketamine Nasal Spray
UK Health Technology Assessment body raises questions over the clinical and cost-effectiveness of Spravato (esketamine).
Is Kratom a Psychedelic Drug?
Technically the answer is no, but subjective experiences may vary.
Positive Effects of Single-Dose Psilocybin Last Nearly 5 Years
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
The Structure and Function of the Serotonin 5-HT2A Receptor
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.
Supportive Context is Associated With Positive Effects From Inhaling 5-MeO-DMT
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...
2005 Literature Review Proposes Serotonin Mediates the Effects of Estrogen
The authors argue that the serotonergic mediation of estrogen has important clinical implications and warrants further investigation.
Vermont Rep. Brian Cina Introduces Bill to Decriminalize Psilocybin, Peyote, Ayahuasca, and Kratom
If passed and signed by Governor Phil Scott, the law will go into effect July 1, 2020.