Serotonin and the Mental Organs Hypothesis
The Mental Organs Hypothesis reconsiders the relationship between 5-HT2 receptors and the qualitative effects of psychedelics.
Articles
Engineering Psychoplastogens: Toward a Safer Alternative for Treating Depression
Identification of psychoplastogenic isoDMT analogs is a concrete step forward in using psychedelics for treating patients who suffer from depression.
Researchers Synthesize Novel Compound, Tabernanthalog, a Non-Hallucinogenic Ibogaine Analog
This compound exhibits reduced cardiotoxicity, psychoplastogen characteristics, and potential therapeutic effects in animal models.
Ibogaine vs. Iboga Alkaloids for Treating Addiction
Novel chemical variants of ibogaine may offer therapeutic benefits without severe side effects.
What is the Mystical Experience Questionnaire?
The MEQ is a self-report measure that provides insight into a key aspect of the psychedelic experience.
The Effects of Psilocybin on Morality and Empathy
This study is the first of its kind to suggest that psilocybin enhances emotional empathy but does not affect moral behavior.
Hamilton Morris Synthesizes 5-MeO-DMT in “Pharmacopeia”
“I believe one person can produce enough 5-MeO-DMT to supply everyone that would ever want it.”
Are the Subjective Effects of Psychedelics Necessary for Their Therapeutic Benefits?
Researchers at the forefront of psychedelic science put forth their arguments in this important debate.
The Top 10 Psilocybin Research Papers of 2020
Changes in brain functioning, new synthesis methods, and psychotherapy dominate this year’s most-cited psilocybin papers.
Compassionate Use – Psychedelic Therapy for Those Who Can’t Wait
“Obviously, bureaucracy is not a human being. People have compassion. Bureaucracies don’t always have compassion.' -- Spencer Hawkswell