Even at therapeutic doses, ibogaine may cause potentially life-threatening cardiac arrhythmia. Science is beginning to unravel the pharmacological factors that may underlie ibogaine-induced cardiotoxicity.
New perspectives on whether mystical experiences have a place in psychedelic science.
Although there are distinct differences between our species, the mouse serotonin 2A receptor plays a crucial role in human psychedelic drug research.
Researchers give us some new data on LSD’s chances of causing bad trips, flashbacks, and other adverse effects.
Data released by Filament Health shows why it’s important to understand the basic chemical makeup of magic mushrooms.
Reviewing early research (1895-1975) on changes in auditory perception.
The serotonin 2A receptor is a major player in the psychedelic response, but it may not be the only one involved.
Despite differing pharmacodynamics, ketamine and serotonergic psychedelics may share downstream effects crucial to their rapid and sustained antidepressant activity.
This innovation may pave the way for pharmaceuticals that act like psychedelics at the 5-HT2A receptor but don’t have hallucinogenic effects.
The names may sound familiar, but these compounds reveal more about nature’s complex chemical cocktail in toad venom.