Scientific Research

5-HT2A Virtual Chemical Screen Produces New Candidate Antidepressants

November 10, 2022 - - 1 Comment

The serotonin receptor subtype 5-HT2A is key for the effects of many psychedelic substances in humans, but it is also a major drug target for new antidepressants. However, large challenges have prevented this therapeutic promise from being realised. Overcoming the early bottlenecks, innovative drug discovery methods have produced two new compounds with potential for therapeutic development.