The head-twitch response in rodents indicates stimulation of the 5-HT2A receptor. This knowledge helps researchers design experiments to understand how psychedelics work.
This is the first time researchers have correlated psilocin bound to 5-HT2A receptors in the brain, levels of psilocin in the blood, and subjective experiences.
Magic mushrooms may be synthesizing this newly-discovered compound from baeocystin.
Psilocybin produces more insightful and mystical experiences, but dextromethorphan causes greater feelings of disembodiment.
Data analysis and gene expression maps confirm the role of the 5-HT2A receptor in the effects of LSD.
Psilocin makes neurons grow faster and produce more connections.
A study in the mouse brain shows serotonin neurons are organized into parallel subsystems.
St Vincent's Hospital of Melbourne, Australia will begin treating patients in April
The FDA will work to expedite the development and review of the drug so it can get to patients as soon as possible.
The metabolism of psilocybin and psilocin is often cited. But, the supporting data are seldom discussed.