Psychedelic drugs like psilocybin and LSD have been investigated for their anti-anxiety (anxiolytic) potential in people with end-of-life anxiety associated with severe illness, but the anxiolytic effects of LSD-assisted therapy had not yet been assessed in patients with anxiety disorders without life-threatening illness.
Psilocybin demonstrated preliminary efficacy for alcohol use disorder in a recent randomized clinical trial. The mechanism may lie in its interaction with glutamate receptors in the reward pathway of the brain.
Dr. Rachel Yehuda shares details about an ongoing clinical trial involving MDMA-assisted psychotherapy to treat post-traumatic stress disorder in veterans.
Psychedelic science operates with an abundance of caution.
A deep dive into the strengths and limitations of the trial.
Was psilocybin really effective for treating depression?
A look back at the therapeutic role of music in psilocybin therapy.
The psychoactive effects of DMT were discovered in 1956 by Dr Szàra.
Psychedelics present unique epistemological and ethical challenges.
Recent antidepressant exposure may reduce the treatment efficacy of MDMA.