Magic Mushroom Formulations Update
Magic mushroom science marches on as understudied psilocybin derivatives start taking center stage.
Biology
Gut Feeling: Links Between LSD, Endocannabinoids, and the Microbiome
In the last 10 years, psychiatric interest in the use of psychedelics, such as psilocybin and LSD, has surged. A new study employed mice to examine how LSD could exert changes on the inflammatory response and the gut microbiome.
Psychedelic Brains In A Dish
Lab grown brains help to shed insight on 5-MeO-DMT mechanisms.
Whole-Body Effects of Psychedelics Part 3 – The Heart
What is known about the divergent roles of the microscopic targets within the cardiovascular system and the cardiac risks versus benefits of psychedelics?
Opening the Mushroom Pharmacopeia: The Case of Norbaeocystin
By engineering E. coli to produce norbaeocystin, researchers seek to settle whether this precursor to psilocybin is itself psychedelic.
The Doors of Expression: LSD Alters Epigenetics and Protein Induction
Psychedelics have demonstrated the potential for rapid, dramatic, and enduring therapeutic effects in people with psychiatric disorders as well as in animal models of these conditions. However, the molecular adaptations in the brain that underlie these profound psychedelic-induced behavioral changes have yet to be defined.
Exploring Ketamine’s Antimicrobial Effects & Fungal Sources: Part 2
As science unravels ketamine’s mechanisms of action to better understand its efficacy as an antidepressant, its antibacterial activity has been probed at the same time. Current research has found a naturally-occurring, fungal origin for the drug, exhibiting antiparasitic properties.
Exploring Ketamine’s Antimicrobial Effects & Fungal Sources: Part 1
As ketamine’s demonstrable therapeutic applications have become ever more popular, earlier research lauding its potential as an antimicrobial and antiparasitic agent has quietly reemerged.
Kambô: Another Psychedelic Amphibian?
Relatively unknown to Western medicine, Kambô is a frog skin secretion with potent, and potentially dangerous physiological and psychological effects.
MDMA-Assisted Psychotherapy for PTSD: Interviewing Dr. Rachel Yehuda
Dr. Rachel Yehuda shares details about an ongoing clinical trial involving MDMA-assisted psychotherapy to treat post-traumatic stress disorder in veterans.