Ketamine Helps People Dislike Themselves Less
New research shows that ketamine reduces self-dislike, loosening the rigid prejudice toward oneself that can constitute depression.
Other Science
Quipazine: A Long-Standing Enigma in Psychedelic Research
The “psychedelic drug” label appears to define a clear-cut category. However, there are lesser-known research chemicals that depict more diffuse boundaries in this classification.
Metabolizing DMT – The Differences Between Oral Administration and Smoking
Research is indicating that a less efficient metabolic pathway plays a role in DMT’s psychoactivity.
Hamilton Morris on 5-MeO-DMT, the Entourage Effect, and Protecting Toads
Morris has insightful ideas for studying psychedelic toad secretions while prioritizing the conservation of toads.
G Protein-Coupled Receptors: What Are They and How Do They Work?
GPCRs play a major role in the psychedelic effect. They also have qualities that make them ideal targets for drug development.
Understanding Drug Potency and Its Importance in Psychedelic Research
Understanding the potency of the compounds in nature’s cocktails is essential for formulating effective doses.
5 Fast Facts You May Not Know About Albert Hofmann and LSD
Hofmann’s work with LSD started with purpose, faded away, and then went down in history.
2020 State of the Art of Psychedelic Technology – Where Is It Heading?
In 2020, the path forward for psychedelic drug research goes in several directions.
Emotional Adjustment: The Modulatory Influence of Psilocybin on the Amygdala
Recent research suggests that psilocybin causes changes in amygdala activity opposite to those seen in conventional antidepressant treatment.
The Structure and Function of the Serotonin 5-HT2A Receptor
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.