Insight into Ayahuasca’s Antidepressant Effects
Research indicates that C-Reactive Protein may play a vital role in combating Treatment-Resistant Depression.
Neurochemistry
Serotonin and the Mental Organs Hypothesis
The Mental Organs Hypothesis reconsiders the relationship between 5-HT2 receptors and the qualitative effects of psychedelics.
Researchers Synthesize Novel Compound, Tabernanthalog, a Non-Hallucinogenic Ibogaine Analog
This compound exhibits reduced cardiotoxicity, psychoplastogen characteristics, and potential therapeutic effects in animal models.
Are the Subjective Effects of Psychedelics Necessary for Their Therapeutic Benefits?
Researchers at the forefront of psychedelic science put forth their arguments in this important debate.
Editor’s Choice Award – Best Psychedelic Chemistry/Synthesis Study of 2020
This study provides meaningful access to some lesser-known magic mushroom compounds and conducts biological testing on them for the first time.
Methoxetamine: Cousin of Ketamine
The characterization of methoxetamine, a ketamine analog, and how its action on the serotonin system sets it apart.
Insights Into the Neurophysiology of Tryptamine-Derived Hallucinogens
Brain imaging research reveals where psychedelic compounds such as psilocybin and LSD manifest their effects.
It Takes Guts: Psychedelic Treatment Approaches to Autoimmune Disorders
There is much research into psychedelic treatment of mental disorders, but psychedelics might be effective in treating autoimmune disorders as well.
How to Change Your Ability to Change
The monoamine hypothesis of depression leaves many patients without effective help. It’s time for a paradigm shift, and psychedelics may be leading the way.
What is the Default Mode Network?
A default level of brain activity sheds light on the source of consciousness and mechanisms of ego death.