First Proof that Psilacetin is a Prodrug of Psilocin
Nichols and Frescas’ 1999 hypothesis becomes a validated scientific theory.
Neurochemistry
Study of Norpsilocin Derivatives Reveals the Potential Importance of Monoalkyl Tryptamines
Norpsilocin is not psychoactive but minor changes to its chemical structure translate into major changes in its pharmacology.
Psychedelic or Not: Of Mice, 5-HT2A Agonists, and Head Shakes
More than half a century since its development, the head-twitch response assay still plays a prominent role in psychedelic research.
MDMA-Assisted Psychotherapy for PTSD: Interviewing Dr. Rachel Yehuda
Dr. Rachel Yehuda shares details about an ongoing clinical trial involving MDMA-assisted psychotherapy to treat post-traumatic stress disorder in veterans.
Editor’s Choice Award 2021-Best Study on Psychedelics and Neuroplasticity
The pace of psychedelic research continued its acceleration during 2021, culminating in several fascinating and groundbreaking studies. As the year comes to a close, Psychedelic Science Review is acknowledging some...
Editor’s Choice Award 2021-Best Study on Psychedelics and Pharmacology
The pace of psychedelic research continued its acceleration during 2021, culminating in several fascinating and groundbreaking studies. As the year comes to a close, Psychedelic Science Review is acknowledging some...
Editor’s Choice Award 2021-Best Study on Psychedelics and Neurochemistry
The pace of psychedelic research continued its acceleration during 2021, culminating in several fascinating and groundbreaking studies. As the year comes to a close, Psychedelic Science Review is acknowledging some...
The Serotonin 5-HT2A Receptor: From Mice to Humans
Although there are distinct differences between our species, the mouse serotonin 2A receptor plays a crucial role in human psychedelic drug research.
The Therapeutic Effects of Psychedelics: 2A or Not 2A?-Part 2
Some studies reveal that serotonin 2A receptor activation may not be necessary for the potential therapeutic effects of psychedelics.
Are Prodrugs the Next Wave of Psychedelic Drug Development?
The path toward therapeutic psychedelic-based drugs is becoming clearer as scientists understand more about how they are processed in the body.