The Nuances of Ketamine’s Neurochemistry
What's similar and different about the R and S isomers of ketamine?
Neurochemistry - Page 5
The Structure-Activity Relationship of Psilocybin Analogs
Seventeen 4-acetoxy and 4-hydroxy substituted derivatives “have psilocybin-like pharmacological properties.”
‘Pharmacopeia’ Season Finale Features Cutting Edge Psychedelic Research
“We have some [compounds] now that are unlike anything you’ve ever seen before.”
The Role of Oxytocin in MDMA’s Prosocial Effects
The link between oxytocin and MDMA is less straightforward than once thought.
Pharmacological Testing in Psychedelic Research
Receptor testing of the affinity and potency of compounds is a critical component of psychedelic research.
Ayahuasca’s Role in the Entourage Effect and Depression
Research suggests that DMT may not be the only compound responsible for ayahuasca's effects.
Insight into Ayahuasca’s Antidepressant Effects
Research indicates that C-Reactive Protein may play a vital role in combating Treatment-Resistant Depression.
Serotonin and the Mental Organs Hypothesis
The Mental Organs Hypothesis reconsiders the relationship between 5-HT2 receptors and the qualitative effects of psychedelics.
Researchers Synthesize Novel Compound, Tabernanthalog, a Non-Hallucinogenic Ibogaine Analog
This compound exhibits reduced cardiotoxicity, psychoplastogen characteristics, and potential therapeutic effects in animal models.
Are the Subjective Effects of Psychedelics Necessary for Their Therapeutic Benefits?
Researchers at the forefront of psychedelic science put forth their arguments in this important debate.