The Structure-Activity Relationship of Two Kratom Compounds
Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
Articles - Page 3
UK Assessment Agency Rejects Spravato Ketamine Nasal Spray
UK Health Technology Assessment body raises questions over the clinical and cost-effectiveness of Spravato (esketamine).
Is Kratom a Psychedelic Drug?
Technically the answer is no, but subjective experiences may vary.
Positive Effects of Single-Dose Psilocybin Last Nearly 5 Years
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
The Structure and Function of the Serotonin 5-HT2A Receptor
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.
Supportive Context is Associated With Positive Effects From Inhaling 5-MeO-DMT
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...
2005 Literature Review Proposes Serotonin Mediates the Effects of Estrogen
The authors argue that the serotonergic mediation of estrogen has important clinical implications and warrants further investigation.
Vermont Rep. Brian Cina Introduces Bill to Decriminalize Psilocybin, Peyote, Ayahuasca, and Kratom
If passed and signed by Governor Phil Scott, the law will go into effect July 1, 2020.
City of Santa Cruz, California Decriminalizes Naturally-Occurring Psychedelics
On January 28, 2020, members of the Santa Cruz City Council voted unanimously to decriminalize the possession and cultivation of a wide variety of naturally-occurring psychedelic plants and fungi. The...
2000 Study Finds Estrogen + Progesterone Increases Cortical 5-HT2A Receptor Binding Potential in Postmenopausal Women
The hormone combination increased 5-HT2A binding potential over 20%.