Czechoslovakian researchers tested the disruption of auditory event-related evoked action potentials (ERPs) in volunteers experiencing psychosis induced with psilocybin. They found pre-attentive cognition was not affected, but higher-order cognition and early perceptual levels were significantly disrupted by psilocybin. These results suggest the altered information processing seen in psychosis and schizophrenia may be related to 5-hydroxytryptophan 2A receptors.
Study Finds Psilocybin Alters Information Processing via 5-HT2A Receptor
Using psilocybin, researchers determined that the altered information processing in the brains of people with psychosis and schizophrenia may be related to 5-hydroxytryptophan receptors.