
Researchers at the Johns Hopkins School of Medicine studied the effects of psilocybin on treating anxiety and depression in patients with life-threatening cancer. Fifty-one patients received very low (1 or 3 mg/70 kg) or high dose (22 or 30 mg/70 kg) psilocybin and underwent a 6 month follow up. Patients in the high dose group saw large decreases in depressed mood and anxiety. They also had increases in quality of life, optimism, meaning of life, and a decrease in death anxiety.