To begin, the center will focus on researching the effects of psilocybin.
UK Health Technology Assessment body raised questions over the clinical and cost-effectiveness of the drug.
Dr. Michael Mithoefer of the Department of Psychiatry and Behavioral Sciences will lead the center.
The distinguished psychedelic researcher Dr. Roland Griffiths is directing operations at the center.
The new Imperial Centre for Psychedelic Research is the first of its kind in the world.
The Foundation works to reform global drug policy and support scientific research into psychoactive substances.
"Advancing studies on psilocybin for treatment of addictions and other mental disorders, with the highest standards of scientific research."