This new solvate of psilacetin could provide new properties like solubility, leading to new opportunities for formulating drugs.
Published in Acta Crystallographica, researchers unveiled a new crystalline form of psilacetin, a prodrug of psilocin (psilacetin is also known as O-acetylpsilocin and 4-AcO-DMT). Earlier in 2019, the same research team published the crystal structure of 4-AcO-DMT fumarate. The crystal structure in the previous work represents the fumarate salt of psilacetin which was described by David Nichols and Stewart Frescas of Purdue University in 1999. In contrast, this newer psilacetin crystal structure consists of two protonated psilacetin molecules that are charge-balanced by one fumarate dianion.
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