Psilocybin Mindfulness Negatively Correlated with 5-HT2A Binding, Study Finds
Results hint at a possible mechanism for the persistent effect that psilocybin has on mindfulness.
Chemistry - Page 12
Cellular Receptors and Their Role in the Psychedelic Effect
Research is revealing that the psychedelic effect is due to much more than 5-HT2A activation.
Study Shows Norpsilocin is More Potent Than Psilocin at 5-HT2A
Greater potency means doing more with less. But does norpsilocin even have a role in the psychedelic effect?
Scientists Solve Another Crystal Structure of the Psilocybin Analog Miprocin, 4-HO-MiPT
This is the second crystal structure of this compound, providing additional options for developing psychedelics into therapeutic drug formulations.
Study Indicates the Magic Mushroom Compound Baeocystin is Not Psychedelic
Baeocystin does not cause the head twitch in mice, but its metabolite norpsilocin is more potent than psilocin.
Is Ibogaine a Psychedelic Drug?
Yes, based on its effects. But it doesn’t work via the serotonin 5-HT2A receptor like other psychedelics.
Scientists Synthesize and Test the Magic Mushroom Compounds Baeocystin, Norbaeocystin, Norpsilocin, and Aeruginascin
This work is a giant step forward for psychedelic research.
Psychedelics May Aid in Deprogramming Addiction
Recent evidence suggests psychedelics may significantly improve addiction treatment outcomes.
The Structure and Function of the Serotonin 5-HT1A Receptor
Activation of neuronal 5-HT1A receptors causes hyperpolarization and inhibition of cellular signaling.
The Structure-Activity Relationship of Two Kratom Compounds
Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.