The Compounds in Psychedelic Cacti
Mescaline is the best-known phenethylamine in psychedelic cacti; but what about the other “minor” compounds in those cacti?
Chemistry - Page 3
The Therapeutic Effects of Psychedelics: 2A or Not 2A?-Part 2
Some studies reveal that serotonin 2A receptor activation may not be necessary for the potential therapeutic effects of psychedelics.
Are Prodrugs the Next Wave of Psychedelic Drug Development?
The path toward therapeutic psychedelic-based drugs is becoming clearer as scientists understand more about how they are processed in the body.
The Therapeutic Effects of Psychedelics: 2A or Not 2A? – Part 1
The serotonin 2A receptor is a major player in the psychedelic response, but it may not be the only one involved.
Glow Time: PsychLight Brings a Powerful Tool to Psychedelic Research
This innovation may pave the way for pharmaceuticals that act like psychedelics at the 5-HT2A receptor but don’t have hallucinogenic effects.
Scientists Isolate Two New Compounds from Toad Venom
The names may sound familiar, but these compounds reveal more about nature’s complex chemical cocktail in toad venom.
Same But Different: Antidepressant Mechanisms of Psilocybin and Ketamine
Ketamine and psilocybin both exert rapid antidepressant effects. Could these effects be explained by a common mechanism that promotes neurogenesis?
Exploring the Role of Serotonin 2A Activation in LSD’s Effects on Empathy
A recent study indicates that the empathogenic effects of LSD may be independent of serotonin 2A receptor activation.
Enzymes Responsible for DMT Synthesis Coexist in Mammalian Brain Cells
Is DMT produced in the brain? The answer remains unclear, but this 2019 study provides striking evidence supporting the neural-DMT synthesis hypothesis.
More Details on the Psilocybin Mushroom Bluing Reaction
Lenz et al. have revised their bluing theory based on the data from their new study.