Previous research in people with substance use disorders and animal models of drug addiction indicate that classical psychedelics like LSD and psilocybin may reduce drug use and drug-seeking behavior. However, the mechanism of action underlying the anti-addictive effects of psychedelics remains unknown.
Understanding how psychedelics interact with sleep may be important for their use in clinical settings and can provide insight to their underlying mechanisms of action, including those of neuroplasticity.
The pace of psychedelic research continued its acceleration during 2021, culminating in several fascinating and groundbreaking studies. As the year comes to a close, Psychedelic Science Review is acknowledging some...
Reviewing early research (1895-1975) on changes in auditory perception.
Despite differing pharmacodynamics, ketamine and serotonergic psychedelics may share downstream effects crucial to their rapid and sustained antidepressant activity.
This innovation may pave the way for pharmaceuticals that act like psychedelics at the 5-HT2A receptor but don’t have hallucinogenic effects.
A recent study indicates that the empathogenic effects of LSD may be independent of serotonin 2A receptor activation.
Changes in structural neuroplasticity start within 24 hours, are enduring, and may not be solely dependent on 5-HT2A.
Reviewing early research (1895-1975) on changes in visual perception.
Study finds that these altered states are quite similiar.
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