Using Zebrafish as an Experimental Model in Psychedelic Research
These creatures have more in common with humans than one might suspect.
Biology - Page 6
The Biosynthesis of DMT
Understanding this is more important than ever in psychedelic research because scientists think DMT may be an endogenous neurotransmitter.
Beyond Ayahuasca: Therapeutic Effects of N,N-Dimethyltryptamine (DMT)
Researchers are uncovering reasons to think there’s more to DMT than just hallucinations.
What is Allosteric Modulation?
This phenomenon plays an important role in psychedelic drug research and development.
What is Salvia divinorum?
The primary active compound in this plant is more potent than LSD.
The Structure and Function of the Serotonin 5-HT2C Receptor
5-HT2C has a role in the psychedelic effect. Understanding it is essential for harnessing the full benefits of nature’s chemical cocktails.
Hamilton Morris on 5-MeO-DMT, the Entourage Effect, and Protecting Toads
Morris has insightful ideas for studying psychedelic toad secretions while prioritizing the conservation of toads.
Habitat Influences Psychoactive Toad Secretions
Environment and diet may play a role in the alkaloid content of secretions from a Brazilian toad species.
New Biosynthesis of Psilocybin and Related Tryptamines
Researchers took the psilocybin-making genes from P. cubensis and put them into S. cerevisiae allowing them to produce psilocybin, several of its analogs, and a “new to nature” compound.
Psilocybin Superior to Ketamine for Prolonged Antidepressant-Like Effects (Rodent Model)
Results support the idea that serotonin 5-HT2A receptor-directed therapeutic strategies may be superior to ketamine-based treatments for depression.