Understanding Drug Potency and Its Importance in Psychedelic Research
Understanding the potency of the compounds in nature’s cocktails is essential for formulating effective doses.
Biology - Page 7
The Structure and Function of the Serotonin 5-HT2B Receptor
Severe side effects associated with 5-HT2B agonist drugs have dampened the interest of researchers. The therapeutic potential of psychedelics provides incentive for taking it up again.
Cellular Receptors and Their Role in the Psychedelic Effect
Research is revealing that the psychedelic effect is due to much more than 5-HT2A activation.
Is Ibogaine a Psychedelic Drug?
Yes, based on its effects. But it doesn’t work via the serotonin 5-HT2A receptor like other psychedelics.
Scientists Synthesize and Test the Magic Mushroom Compounds Baeocystin, Norbaeocystin, Norpsilocin, and Aeruginascin
This work is a giant step forward for psychedelic research.
The Structure and Function of the Serotonin 5-HT1A Receptor
Activation of neuronal 5-HT1A receptors causes hyperpolarization and inhibition of cellular signaling.
Is Kratom a Psychedelic Drug?
Technically the answer is no, but subjective experiences may vary.
The Structure and Function of the Serotonin 5-HT2A Receptor
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.
What is Kratom?
It is a plant that contains over 40 alkaloid and non-alkaloid compounds, some of which have analgesic and psychoactive properties.
What is Ibogaine?
Ibogaine is a compound found in the leaves of an African shrub called Iboga, and studies indicate it may have anti-addictive properties.