Magic Mushroom Industry Leaders: Top Cultivation Companies
Companies are deconstructing magic mushroom cocktails in search of therapeutic medicines.
Plants, Substances and Products
Magic Mushroom Formulations Update
Magic mushroom science marches on as understudied psilocybin derivatives start taking center stage.
How To Stop A Psychedelic Trip: The Promise of Ketanserin
Psychedelic trips often unfold without issues, but what if a trip needs to be stopped? Drugs such as benzodiazepines and antipsychotics are recommended as rescue medications and have been around for decades. Can ketanserin be used as a more targeted trip stopper?
New 3D Structures of Cannabinoid Receptor Inform Safer Drug Design
Allosteric modulation is a promising way to target the receptors of psychoactive substances, such as CB1R, for therapeutic use. However, it is difficult to design safe, effective allosteric compounds. New high-resolution structures of CB1R provide insight into a way forward for drug discovery.
Opening the Mushroom Pharmacopeia: The Case of Norbaeocystin
By engineering E. coli to produce norbaeocystin, researchers seek to settle whether this precursor to psilocybin is itself psychedelic.
Tackling Trauma with Pharmahuasca and DMT
Psychedelics may hold the key to a novel PTSD treatment.
COMPASS Patent Challenge Targets Crystallography Errors
Experts say COMPASS’ analysis overlooked one of the crystal forms present in their sample.
Psychedelics and Substance Use Disorder: 4000 BCE to Present Day
The therapeutic uses of psychedelics were discovered over 6,000 years ago, but recent scientific exploration brings them to the mainstream.
Editor’s Choice Award 2021-Best Study on Psychedelics and Nature
The pace of psychedelic research continued its acceleration during 2021, culminating in several fascinating and groundbreaking studies. As the year comes to a close, Psychedelic Science Review is acknowledging some...
Ibogaine and Cardiac Arrhythmia: The Heart of the Matter
Even at therapeutic doses, ibogaine may cause potentially life-threatening cardiac arrhythmia. Science is beginning to unravel the pharmacological factors that may underlie ibogaine-induced cardiotoxicity.