Aeruginascin Discovered in Psilocybe Cubensis

This study highlights the importance of understanding the chemical composition of magic mushrooms, including all the active molecules, not just psilocybin.

November 2020

Scientists recently identified the compound aeruginascin in Psilocybe cubensis magic mushrooms.1 In their paper published in Drug Testing and Analysis, Klára Gotvaldová and her research team reported: “[a]n extraction procedure and a UHPLC-MS/MS analytical method for the analysis of psilocybinpsilocinbaeocystinnorbaeocystin, and aeruginascin in fungal biomass.” According to the paper, all these compounds were present in the P. cubensis samples studied. The authors noted that “concentrations of aeruginascin are low and have not been reported before.” This paper is the first report of the compound aeruginascin in any mushroom aside from Inocybe aeruginascens2 or Pholiotina cyanopus.3

    References
  1. Gotvaldová K, Hájková K, Borovička J, Jurok R, Cihlářová P, Kuchař M. Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis. Drug Testing and Analysis. Published online 2020. doi:10.1002/dta.2950
  2. Gartz J. Variation of alkaloid levels in fruiting bodies of Inocybe aeruginascens. Planta Medica. 1987;53(06):539-541. doi:10.1002/hlca.19590420638
  3. Halama M, Poliwoda A, Jasicka-Misiak I, Wieczorek PP, Rutkowski R. Pholiotina cyanopus, a rare fungus producing psychoactive tryptamines. Open Life Sciences. 2014;10(1). doi:10.1515/biol-2015-0005