Kratom Compound Mitragynine Reduces Neuropathic Pain, Study Finds
Pain was inhibited by an α2-adrenoceptor antagonist and reduced by an α1-adrenoceptor antagonist. Opioid receptors may also be involved in the effects.
Scientific Studies - Page 9
Psilocybin Mindfulness Negatively Correlated with 5-HT2A Binding, Study Finds
Results hint at a possible mechanism for the persistent effect that psilocybin has on mindfulness.
Study Shows Norpsilocin is More Potent Than Psilocin at 5-HT2A
Greater potency means doing more with less. But does norpsilocin even have a role in the psychedelic effect?
Scientists Solve Another Crystal Structure of the Psilocybin Analog Miprocin, 4-HO-MiPT
This is the second crystal structure of this compound, providing additional options for developing psychedelics into therapeutic drug formulations.
Study Indicates the Magic Mushroom Compound Baeocystin is Not Psychedelic
Baeocystin does not cause the head twitch in mice, but its metabolite norpsilocin is more potent than psilocin.
Study Participants Experience Psychedelic Effects after Receiving Placebo
A study from McGill University shows that the power of the mind alone can produce a quasi-psychedelic experience.
Scientists Synthesize and Test the Magic Mushroom Compounds Baeocystin, Norbaeocystin, Norpsilocin, and Aeruginascin
This work is a giant step forward for psychedelic research.
The Structure-Activity Relationship of Two Kratom Compounds
Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
Positive Effects of Single-Dose Psilocybin Last Nearly 5 Years
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
Supportive Context is Associated With Positive Effects From Inhaling 5-MeO-DMT
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...