Psychedelics May Relieve Chronic Pain Via Changes in Brain Neuroplasticity
Using psychedelics to treat chronic pain is understudied yet full of potential.
Scientific Studies - Page 8
Noribogaine is More Effective Than Fluoxetine in Reducing Depressive Symptoms in Rat Model
Three doses of fluoxetine were needed to elicit the effects of one dose of noribogaine.
Antidepressant-Like Effect with A Single Dose of Ibogaine and Noribogaine in Rats
This is the first preclinical study to examine the anti-depressive effects of ibogaine and noribogaine.
Scientists Solve the Crystal Structure of the Freebase of 5-MeO-DALT
Understanding the structure of this synthetic analog of 5-MeO-DMT may help explain the effects of naturally occurring chemical cocktails.
Two New Crystalline Forms of Norpsilocin
New crystalline forms of norpsilocin create new options for developing psychedelic drug formulations.
Brain Morphology May Help Explain Differing Psilocybin Experiences
Understanding brain morphology differences may prove essential for creating effective psychedelic drug formulations.
Habitat Influences Psychoactive Toad Secretions
Environment and diet may play a role in the alkaloid content of secretions from a Brazilian toad species.
New Biosynthesis of Psilocybin and Related Tryptamines
Researchers took the psilocybin-making genes from P. cubensis and put them into S. cerevisiae allowing them to produce psilocybin, several of its analogs, and a “new to nature” compound.
Psilocybin Superior to Ketamine for Prolonged Antidepressant-Like Effects (Rodent Model)
Results support the idea that serotonin 5-HT2A receptor-directed therapeutic strategies may be superior to ketamine-based treatments for depression.
Kratom Compound Mitragynine Reduces Neuropathic Pain, Study Finds
Pain was inhibited by an α2-adrenoceptor antagonist and reduced by an α1-adrenoceptor antagonist. Opioid receptors may also be involved in the effects.