Recent evidence suggests psychedelics may significantly improve addiction treatment outcomes.
Recent research suggests that psilocybin causes changes in amygdala activity opposite to those seen in conventional antidepressant treatment.
Activation of neuronal 5-HT1A receptors causes hyperpolarization and inhibition of cellular signaling.
Decriminalize Nature DC is driving the effort to get the initiative on the November ballot.
Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
UK Health Technology Assessment body raises questions over the clinical and cost-effectiveness of Spravato (esketamine).
Technically the answer is no, but subjective experiences may vary.
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...