Even slightly modifying the chemical structure of the compounds in kratom can significantly alter their effects.
UK Health Technology Assessment body raises questions over the clinical and cost-effectiveness of Spravato (esketamine).
Technically the answer is no, but subjective experiences may vary.
After 4.5 years, 60-80% of the study participants with life-threatening cancer still experienced significantly decreased anxiety or antidepressant effects.
The 5-HT2A receptor is central to the effects of many psychedelics, but it may not be the only receptor involved.
A research team including psychedelics expert Dr. Roland Griffiths recently published a study examining how context (the set and setting) impacts the effects of inhaling 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine).1 Previous research strongly...
The authors argue that the serotonergic mediation of estrogen has important clinical implications and warrants further investigation.
If passed and signed by Governor Phil Scott, the law will go into effect July 1, 2020.
On January 28, 2020, members of the Santa Cruz City Council voted unanimously to decriminalize the possession and cultivation of a wide variety of naturally-occurring psychedelic plants and fungi. The...
2000 Study Finds Estrogen + Progesterone Increases Cortical 5-HT2A Receptor Binding Potential in Postmenopausal Women
The hormone combination increased 5-HT2A binding potential over 20%.