What is Salvia divinorum?
The primary active compound in this plant is more potent than LSD.
Neurochemistry - Page 8
Psychedelics May Relieve Chronic Pain Via Changes in Brain Neuroplasticity
Using psychedelics to treat chronic pain is understudied yet full of potential.
Stopping Bad LSD Trips with “Off-Switch” Technology
This technology developed by MindMed and Liechti Lab may help ease some of the concerns surrounding psychedelic therapy.
The Structure and Function of the Serotonin 5-HT2C Receptor
5-HT2C has a role in the psychedelic effect. Understanding it is essential for harnessing the full benefits of nature’s chemical cocktails.
Brain Morphology May Help Explain Differing Psilocybin Experiences
Understanding brain morphology differences may prove essential for creating effective psychedelic drug formulations.
Kratom Compound Mitragynine Reduces Neuropathic Pain, Study Finds
Pain was inhibited by an α2-adrenoceptor antagonist and reduced by an α1-adrenoceptor antagonist. Opioid receptors may also be involved in the effects.
G Protein-Coupled Receptors: What Are They and How Do They Work?
GPCRs play a major role in the psychedelic effect. They also have qualities that make them ideal targets for drug development.
Understanding Drug Potency and Its Importance in Psychedelic Research
Understanding the potency of the compounds in nature’s cocktails is essential for formulating effective doses.
The Structure and Function of the Serotonin 5-HT2B Receptor
Severe side effects associated with 5-HT2B agonist drugs have dampened the interest of researchers. The therapeutic potential of psychedelics provides incentive for taking it up again.
Psilocybin Mindfulness Negatively Correlated with 5-HT2A Binding, Study Finds
Results hint at a possible mechanism for the persistent effect that psilocybin has on mindfulness.