Escalating LSD doses lead to more pronounced subjective and autonomic effects, while pre-administration of ketanserin prevents the effects of a high LSD dose.
This compound may be more ubiquitous than scientists originally thought. But no one has really gone looking for it yet.
According to IIT, psychedelics cause concepts to form more links with each other than usual. This might explain several phenomena observed in psychedelic mind-states.
New research shows that ketamine reduces self-dislike, loosening the rigid prejudice toward oneself that can constitute depression.
Experiential avoidance is one transdiagnostic process that may be implicated in the therapeutic benefits of psychedelics.
While ketamine produces a whole symphony of effects in the brain, surprisingly, a localized neural oscillation in a lesser-known area of the brain is enough to cause feelings of dissociation.
Both have long-lasting positive effects on mood, social skills and neuroplasticity. Combining them may potentiate and prolong mutual therapeutic effects.
This study provides the first preliminary quantitative exploration of the psychological effects of psychedelics in individuals with a self-reported diagnosis of an eating disorder.
"Now we know how psychedelic drugs work – finally! We might be able to switch some effects on while keeping others off."
Stronger binding interactions between MDMB-Fubinaca and CB1 may explain why some synthetic cannabinoids cause dangerous effects.